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DAY 2: Introduction and Plenary Session

Congress Opening Remarks by James Markmann and Hussein Khambalia
12:00 - 12:45 View From the Patient's perspective: Successes and challenges related to Beta Cell Replacement therapies past, present and future
Karin Hehenberger, United States
Perspective from pancreas transplant patient
Norma Stephenson, United States
Perspective from Islet Transplant Patient
Thomas WH Kay, Australia
Islet Transplantation - the patient's view
Dixon B Kaufman, United States
Perspective from transplant surgeon

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Parallel Sessions

12:45 - 13:45 View Innovation Showcase in Pancreas Transplantation
Gabriel Oniscu, United Kingdom
Normothermic Regional Perfusion
Matthew Cooper, United States
Pancreas Transplantation for T2D
Fabio Vistoli, Italy
Pisa Consensus Conference Report: Summary of findings
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12:45 - 13:45 View Long-term Islet Transplant Outcomes: Keys to long term success and future challenges
Thierry Berney, Switzerland
GRAGIL Islet Transplant Experience
Paul Johnson, United Kingdom
Lessons learned from the UK Islet Transplant Consortium
Francois Pattou, France
Islet Transplantation in Lille, France
Lawrence G. Hunsicker, United States
Impact of Achieving Insulin Independence with Islet Transplantation
Bernhard J. Hering, United States
Collaborative Islet Transplant Registry (CITR)

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LIVE Discussion Rooms Breakouts

Join the discussion in one of the breakout sessions and have the opportunity to share best practices, voice your opinion and actively engage with facilitators and other participants
13:50 - 14:20 View Career tips for young scientists
Hanne HS Scholz, Norway
Facilitator
Giuseppe Orlando, United States
Facilitator
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13:50 - 14:20 View Human Islet Isolation: Technical Q&A
Robert McCarthy, United States
Facilitator
Appakalai Natarajan Balamurugan, United States
Facilitator
Doug O'Gorman, Canada
Facilitator

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This interactive session will provide a forum for human islet isolators to increase their knowledge of the unwritten technical issues encountered during the islet isolation process (organ procurement, tissue preparation, tissue dissociation, islet purification, islet characterization, islet delivery).
Those interested in participating are encouraged to review in advance the slide deck that consolidates a list of the more commonly asked questions to our experts by islet isolators.
If you have any questions that you would like to see addressed during the session, please email them in advance to the moderator rcmccarthy@vitacyte.com or you can submit them during the breakout session.
Our experts will be live during the session to reply to your questions or clarify their answers from Q&As on the slide deck.
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13:50 - 14:20 View Pancreas Transplantation Program Development - Recipes for Success
Peter Abrams, United States
Facilitator
Joseph R. Scalea, United States
Facilitator
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13:50 - 14:20 View Overcoming challenges for stem cell differentiation to islets
Valeria Sordi, Italy
Facilitator
Nathaniel Hogrebe, United States
Facilitator
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13:50 - 14:20 View Managing the challenging patient after pancreas and islet transplantation: Focus on key challenges-faltering compliance, weight gain, hyperglycemia, declining C-peptide, and opportunistic infections
Nancy A Radke, United States
Facilitator
Lilian Penfornus, Switzerland
Facilitator
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Parallel Sessions

14:20 - 15:20 View Long-term Outcomes of Pancreas Transplantation; Tips, Tricks and Wisdom for Handling Challenging Pancreas Transplant Complications
Angelika C. Gruessner, United States
Pancreas Transplant Registry Update: Insights and Long term results
Ty B. Dunn, United States
Case presentations with Panelists
Stephen T. Bartlett, United States
Panelist
Thierry Berney, Switzerland
Panelist
Jonathan A Fridell, United States
Panelist
Pablo D Uva, Argentina
Panelist
This multi-format session will begin with a presentation on “Pancreas Transplant Registry Update: Insights and Long-term Results” and then continue with a panel discussion of challenging cases by an international panel of pancreas transplant surgeons
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14:20 - 15:20 View Enabling Technologies for Beta Cell Transplantation
Klearchos K. Papas, United States
Measuring and Combating Hypoxia
Cherie Stabler, United States
Microphysiological Systems, Matrix and Islet Physiology
Jordan Miller, United States
Advances in 3D bioprinting of vasculature for tissue engineering

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Networking Break

15:25 - 15:40 View The ultimate IPITA Trivia
Jonathan A Fridell, United States
Facilitator
Hussein Khambalia, United Kingdom
Facilitator
Have fun and test your knowledge at the ultimate IPITA Trivia Quiz!
We’ll be asking questions covering everything from basic science to general knowledge. It’s time to prove your expertise, challenge your colleagues, and above all have a good time!

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Oral Abstract Sessions

15:45 - 17:05 View Clinical Islets
Mikael Chetboun, France
Association of Primary Graft Function and 5-year outcomes of islet transplantation: An international study from the Collaborative Islet Transplant Registry (CITR)
Piotr J Bachul, United States
Favorable 5-year follow up outcomes after islet transplantation in patients with type 1 diabetes mellitus at University of Chicago
David A Baidal, United States
Predictive Value of C-peptide Measures for Clinical Outcomes of Islet Transplantation in Type 1 Diabetes: A Report from the Collaborative Islet Transplant Registry (CITR)
Marcus Bergström MD, Sweden
Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation
Mehdi Maanaoui, France
Impact of HLA donor specific antibodies in the era of cell therapy: clinical trajectories in islet allotransplantation illustrate a challenging model
Joana Lemos, United States
Effect of HLA Matching on Long Term Islet Allograft Function
Prathab Balaji Saravanan, United States
DAMP Proteins Released via Exosomes during Islet Isolation Affects TPIAT outcomes
Srividya Vasu, United States
Association of circulating miRNAs with clinical parameters in patients undergoing Total Pancreatectomy with Islet Auto-Transplantation (TPIAT)
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15:45 - 17:05 View Clinical Pancreas Transplantation - Part 1
Sandesh Parajuli, United States
The presence of donor-specific antibodies around the time of pancreas graft biopsy with rejection is associated with an increased risk of graft failure
Marcelo Perosa MD, Brazil
Over 1,000 pancreas transplantation in a Latin American Program
Eric Martinez, United States
Does Type of Diabetes affect Rejection, Infection, and Surgical Outcomes after Simultaneous Pancreas-Kidney Transplantation?
Neeraj Singh, United States
Outcomes of Simultaneous Kidney-Pancreas Transplantation in Patients with Type-1 and Type-2 Diabetes Mellitus
Hosein Shokouh-Amiri, United States
Q&A live discussion (replacement for Neeraj Singh)
Lucija A Kovacic, United Kingdom
Can cardiopulmonary exercise test results predict the length of critical care stay in patients undergoing simultaneous kidney pancreas transplant?
Angelika C. Gruessner, United States
The impact of obese deceased donor on outcome in simultaneous pancreas/kidney transplants - A registry analysis
Enrique Montagud-Marrahi, Spain
Impact of preemptive transplantation on long-term outcomes after simultaneous pancreas-kidney transplantation
Pedro Ventura Aguiar, Spain
Q&A Live Discussion (replacement for Enrique Montagud-Marrahi)
Marcelo Perosa MD, Brazil
Experience of 91 pancreas retransplants and predictors of outcome
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15:45 - 17:05 View Stem Cells and Related Topics
Purushothaman Kuppan, Canada
Co-localized immune protection using cyclosporine A eluting micelles in a murine islet allograft model
Dario Gerace, United States
Engineering immune-evasive human stem cell derived-islet cells
Valentina Zamarian, Italy
Treating iPSC-derived β cells with monoclonal antibody Brentuximab reduces the risk of teratoma upon transplantation
Paraish Misra, Canada
Characterizing the therapeutic potential of human pluripotent stem cell-derived islet-like cells lacking cell-surface HLA expression
Yasaman Aghazadeh, Canada
Microvessels support the in vivo engraftment and function of pancreatic cells in cell replacement therapy
David A Alagpulinsa, United States
Long-term functional survival of human stem cell-derived islets microencapsulated in alginate with CXCL12 in non-human primates without immunosuppression
Sara D Sackett, United States
An inducible genome engineering approach for preventing immune rejection of hESC-derived beta cells
Jacqueline Burke, United States
Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability
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Richard C. Lillehei Memorial Award Lecture

17:10 - 18:00 View Richard C. Lillehei Memorial Award Lecture
Giuseppe Orlando, United States
Introduction of Awardee
Robert J Stratta, United States
Pancreas Transplantation for Diabetes: A Half-Century Odyssey and Beyond
A biennial award given to an outstanding clinician and/or scientist for their substantial contributions towards advancing the field of pancreas transplantation
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Networking Break

18:00 - 19:00 Join us for a virtual hangout!
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